Precisely Universally Conserved Amino Acid Residues
Families of homologous proteins from 45
complete genomes representing 31 major phylogenic lineages were examined for
amino acids which were exactly conserved in multi-sequence alignments.
A total of 256 Putatively Universally Conserved Positions (PUCPs) were found
in 32 protein families. PUCPs represent the precise preservation of
information across billions of years and billions of billions of germ-line
replications in independent lineages spanning very nearly all organisms that
have ever lived. It is believed that PUCPs will prove valuable for
focusing attention on the very most critical protein-based constraints that
underlie life itself and that they have far reaching philosophical
implications (which are developed under the next topic).
Evidence that Life on Earth is a product of Intelligent
The available evidence relevant to the
Directed Panspermia theory advanced by Crick, F.H.C. and Orgel, L. (1973)
Icarus 19, 341, will be reviewed. This topic was previously considered
in the book Crick, F.H.C. (1981) Life Itself, (Simon and Schuster, New York).